박종철 / PARK, Jong-Chul
교수

Department / Institute / Center :
Medical Engineering
연세의료기술품질평가센터

Contact Information

Phone +82-2-2228-1917 Email parkjc@yuhs.ac Website

Educational Background

Undergraduate Education B.S., Department of Biochemistry, Yonsei University, 1987 M.S., Department of Public Health, Seoul National University, 1990
Final Degree (University, Major) Ph.D., Department of Biotechnology, Tokyo University of Agriculture & Technology, 1995
Overseas Training (Institute, Supervisor) Division of Microbiology, National Institute of Health Sciences,
Kosuke Takatori, PhD, 1995-1996

Professional Societies and current positions

한국생체재료학회, 편집이사
Biomedical Materials, Editorial Board

Research Area(s)

Translational research, Medical devices
Research Field Biological evaluation of medical devices
Bioactivity evaluation of natural products
Cell migration assay
Surface modification of biomaterials
Development of physical sterilization method
Diseases Wound healing, Angiostenosis, Bone defect

Possible Collaboration 천연생리활성물질이 적용된 stent 및 인공혈관의 개발 및 평가
조직재생의 세포이동 제어 이해를 위한 프로그램 개발
의료기기의 전임상 평가
인공피부 개발을 위한 효능 물질 탐색 및 효과 연구

Research Methods

- Cell culture (endothelial cell, smooth muscle cell, fibroblast cell, keratinocyte cell, osteoblast cell, chondrocyte cell, macrophage cell, adipose derived stem cell, mesenchymal stem cell, etc.)
- Animal experiment (wound healing model using nude mouse, intimal hyperplasia model using rat and rabbit, bone defect model)
- Fabrication of degradable polymer sheet using electrospining method
- RT-PCR, western blotting, immunofluorescence assay, immunohistochemistry assay, ELISA assay
- confocal microscopy, fluorescence microscopy
- FACS analysis, apoptosis assay
- Detection assay of Osteoblast differentiation (ALP, Alizarin Red assay, Von kossa assay etc)
- Biological safety evaluation assay (Cytotoxicity, Ames test, sister chromatide exchange assay, micronucleus assay, irradiation assay, systemic toxicity, etc.)

Lab.

연구실사이트 바로가기
Location of Office 제중관 1층 의학공학교실
Location of Lab. 제중관 1층 연세의료기술품질평가센터 실험실
Contact person Name: 이미희 박사 / Tel: 2228-1924 / E-mail: : LEEMH1541@yuhs.ac

Major Published Articles and Books

1) lee MH, Han D-W, Hyon S-H, Park J-C. Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB. Apoptosis 16(1), 75-85. (2011)
2) Han D-W, Lee MH, Kwon BJ, Kim H-L, Hyon S-H, Park J-C. Differential effect of Epigallocatechin-3-gallate on migration of vascular endothelial cells vs. vascular smooth muscle cells. Molecules 15(11), 8488-8500. (2010)
3) Woo YI, Park BJ, Kim H-L, Lee MH, Kim J, Yang Y-I, Kim JK, Tsubaki K, Han D-W, Park J-C. The biological activities of (1,3)-(1,6)-β-D-glucan and porous electrospun PLGA membranes containing β-glucan in human dermal fibroblasts and adipose tissue-derived stem cells. Biomedical Materials 5(4), 044109 (8pp). (2010)
4) Lee MH, Park BJ, Jin SC, Kim DH, Han I, Kim J, Hyun SO, Chung K-H, Park J-C. Removal and sterilization of the biofilms and planktonic bacteria by microwave-induced argon plasma at atmospheric pressure. New Journal of Physics 11, 115022. (2009)