서활 / SUH, Hwal
교수

Department / Institute / Center :
Tissue Regenerative Medicine Lab. Dept. of Medical Engineering
재생의학연구실
의학공학교실

Contact Information

Phone +82-2-2228-1918 Email hwal@yuhs.ac Website

Educational Background

Undergraduate Education D.D.S. Yonsei University College of Dentistry, 1978
Final Degree (University, Major) Ph.D. Osaka University, 1992. (Biomateirals for Medicine)
Overseas Training (Institute, Supervisor) Researcher, Columbia Institute of Materials Science & Technology, 1985-1987.
Visiting Professor of Regenerative Medical Engineering, Institute for Frontier Medicine, Kyoto University, 2010.

Professional Societies and current positions

Permanent Member, International Scientific Committee, International Conference of Cell and Stem Cell Engineering.
Convener, International Standard Organization(ISO)/ Technical Committee 150 (Surgical Implant)/ Subcommittee 7 (Tissue Engineered Medical Products)/ Working Group 2 (Safety).

Research Area(s)

Translational research, Clinical research
Research Field Design of Therapeutic Cells including stromal and stem cells manipulation.
Hybridization of Cells with biological materials such as extracellular matrix.
Evaluation of in vitro and in viivo efficacy of the cell-based implants
Diseases Soft and Hard Tissue (bone, cartilage, skin, trachea, esophagus, liver, pancreas) Regeneration
Possible Collaboration Stem cells manipulation (Stromal and induced Pluripotent cells).
Gene modification for therapeutice cells.
Hybridization of cells with biomaterials for implantation.
Evaluation of in vitro and in viivo efficacy of the cell-based implants.

Research Methods

Viral and non-viral vector design for gene transfection to produce therapeutic cells.
Synthesis of artificial extracellular matrix using natural and/or non-natural biomaterials.
Hybridization of therapeutic cells with artificial extracellular matrix to produce the cell based implants.
In vitro and in vivo safety analysis of the cell based implants

Lab.

연구실사이트 바로가기
Location of Office 제중관 1층
Location of Lab. 의학공학교실 E 실험실
Contact person Name: 김재형 (박사 5학기 / Tel: 2228-1929 / E-mail: : jaehkim@yuhs.ac

Major Published Articles and Books

1) Collagen Fabrication for the Cell-based Implants in Regenerative Medicine". 2008, Bioengineering in Cell and Tissue Research, p159-192, ISBN 978-3-540-75408-4, Springer, Heidelberg, Germany
2) Therapeutic Potential of Bone-Marrow-Derived Mesenchymal Stem Cells Differentiated with Growth-Factor-Free Coculture Method in Liver-Injured Rats. 2010, Tissue Engineering: Part A, 16:2649-2659.
3) Adipose tissue engineering using mesenchymal stem cells attached to injectable PLGA spheres. 2005, Biomaterials. 26(29): 5855-5863.
4) Sustained release of ascorbate-2-phosphate and dexamethasone from porous PLGA scaffolds for bone tissue engineering using mesenchymal stem cells. 2003, Biomaterials, 24(25):4671-4679.
5) Characterization of Porous Collagen/Hyaluronic Acid Scaffold Modified by 1-ethyl-3(3-dimethylaminopropyl) carbodiimide Cross-linking. 2002, Biomaterials, 24:1205-1212.