김현옥 / KIM, Hyun Ok
교수

Department / Institute / Center :
Department of Laboratory
Medicine/Severance Hospital/Cell
Therapy Center

Contact Information

Phone +82-2-2228-2444 Email hyunok1019@yuhs.ac Website

Educational Background

Undergraduate Education M.D., Yonsei University College of Medicine, 1982
Final Degree (University, Major) Ph.D., Graduate School, Yonsei University, 1990
Overseas Training (Institute, Supervisor) Johns Hopkins Medical Institute, Dept.of Transfusion Medicine
1993-1995

Professional Societies and current positions

Korean Society of Transfusion Medicine : Chairman of the Board (2005-2008)
International Society of Stem Cell Research (a member of TFT of ISSCR guidelines for
clinical translation of stem cells)
Scientific Advisory Board
Academic consultant of Korean Red Cross Blood Research Center from 1989
A council member of Nation Blood Safety and Control Advisory Committee since 2004
A member of Advisory Committee in association with the Korean FDA since 2005.
Vice director of Blood Safety Improvement TFT, Korea

Research Area(s)

Translational research, Clinical research
Research Field Blood safety for transfusion
RBC production from stem cells
Cell banking : mesenchymal stem cells Endothelial progenitor cells etc.
Hematopoietic stem cell transplantation : cell processing
Diseases Oncohematologic malignancy, Candidate diseases for stem cell therapy (Parkinson’s disease, congestive heart failure, Stroke, Spinal cord injury, Alzheimer disease etc)
Possible Collaboration 진단검사의학과에 검사하고 남은 잔여검체를 이용한 연구 (Biomarker detection, 시약기능 평가 등)
세포치료센터에 Banking 되어 있는 인체조직 유래 stem cell 을 이용한 공동연구
인체 주입 가능한 세포치료제 생산 (MSCs Hmeatopoietic stem cells, CD34+ cells etc)
세포치료센터 세포 생산 시설 사용하는 공동 연구
연대공대(김은경, 정효일, 변재철), 생명공학연구원(박병철) KIST(정병화) 와 공동연구 수행 중

Research Methods

Leukapheresis (Cell collection from patients or voluntary donor)
Cell sorting : MiniMACS, Elutra
Cell culture
MSC isolation from mouse, human bone marrow
그외 immunologic diagnostic tool 모두 가능

Lab.

연구실사이트 바로가기
Location of Office 세브란스병원 진단검사의학과 (82444)
Location of Lab. 임상연구센터 101호(82797)
Contact person Name: 김은해 (연구조교수) / Tel: 2228-2797 / E-mail:

Major Published Articles and Books

Baek EJ, You J, Kim MS, Lee SY, Cho SJ, Kim Kim HO. Enhanced production of RBCs in suspension by electrostatic interactions with culture plates. Tissue Engineering 2010 16: 1325-1334.
Maeng Y, Cho SW, Kim HO, Kim JH. Culture of human mesenchymal stem cells using electrosprayed porous chitosan microbeads. J Biomedi Mater Res 2010 92A:869-876
Kim HJ, Kim HO, Lee K, Baek EJ, Kim HS. Two-step maturation of immature DCs with proinflammatory cytokine cocktail and poly(I:C) enhances migratory and T cell stimulatory capacity. Vaccine 2010:28:2877-2886
You J, Heo HS, Lee J, Kim H, Kim HO, Kim E. A fluorescent polymer for patterning of mesenchymal stem cells. Macromolecules 2009 42:3326-32
Baek EJ, Kim H, Kim J, Kim NJ, Kim HO. Stroma-free mass production of clinical-grade red blood cells by using the Pluronic F68 as an erythrocyte survival enhancer. Transfusion 2009 :49:2285-95