김태일 / KIM, Tae Il
부교수

Department / Institute / Center :
Department of Internal Medicine, Division of Gastroenterology / Institute of Gastroenterology

Contact Information

Phone +82-2-2228-1965 Email taeilkim@yuhs.ac Website

Educational Background

Undergraduate Education Feb. 1991, Medical Degree,Yonsei University College of Medicine, Seoul
Final Degree (University, Major) Feb. 2002, Ph. D. course of Medical science,Graduate School, Yonsei University, Seoul
Overseas Training (Institute, Supervisor) Aug. 2006~Jul. 2008, Research fellow, Post-doc, Division of Gastroenterology, Vanderbilt University Medical Center, TN, USA

Professional Societies and current positions

Korean Society of Gastroenterology
Korean Society of Gastrointestinal Endoscopy, Academic Committee
Korean Association for the Study of Intestinal Disease,
American Gastroenterology Association
American Association for Cancer Research

Research Area(s)

Basic research, Clinical research, Medical devices
Research Field Colorectal carcinogenesis, cancer stem cell and microenvironment
Intestinal stem cell and mesenchymal stem cell in inflammatory bowel disease
Gut flora (Probiotic)
Clinical study for IBD treatment and colorectal neoplasia
Colonoscopy and endoscopic device (colon stent)
Diseases Colorectal cancer and polyp
Inflammatory bowel disease (Crohn’s disease, Ulcerativel colitis, Intestinal Bechet)
Possible Collaboration Intestinal stem cell, cancer stem cell and colorectal carcinogenesis
Mesenchymal stem cell treatment
Regulation of inflammation in inflammatory bowel disease
Gut flora
Endoscope and endoscopic device (colon stent)

Research Methods

Isolation of colon cancer stem cell
Immunohistochemical stain, WB, RT-PCR for cancer stem cell markers
Isolation of mesenchymal stem cells
Differentiation model of colon epithelial cells

Lab.

연구실사이트 바로가기
Location of Office 내과학교실 313호
Location of Lab. 임상의학연구센터 4층 403호
Contact person Name: 권지희 / Tel: 02-2228-2812 / E-mail: KWONJH83@yuhs.ac

Major Published Articles and Books

1.Comparison of a newly designed double-layered combination covered stent and D-weave uncovered stent for decompression of obstructive colorectal cancer: a prospective multicenter study. Dis Colon Rectum. 2010 Aug;53(8):1190-6.

2.Adherens junction-dependent PI3K/Akt activation induces resistance to genotoxin-induced cell death in differentiated intestinal epithelial cells. Biochemical and Biophysical Research Communications 2009. Jan 23;378(4):738-743

3.Effect of Lactobacillus GG and conditioned media on IL-1beta-induced IL-8 production in Caco-2 cells. Scand J Gastroenterol. 2008;43:938-47

4.Thalidomide destabilizes cyclooxygenase-2 mRNA by inhibiting p38 mitogen-activated protein kinase and cytoplasmic shuttling of HuR. Eur J Pharmacol. 2007 Mar 8;558(1-3):14-20.

5.Cellular differentiation-induced attenuation of LPS response in HT-29 cells is related to the down-regulation of TLR4 expression. Biochem Biophys Res Comm 2005;337:457-463.

6.The Role of Mitogen-activated Protein Kinases and Their Relationship with NFB and PPAR in Indomethacin-induced Apoptosis of Colon Cancer Cells. Ann. N.Y. Acad. Sci. 2002; 973:241-245