황기철 / Ki-Chul Hwang
교수

Department / Institute / Center :
Severance Biomedical Science Institute, Yonsei Cardiovascular Research Institute
Brain Korea 21 Project for Medical science

Contact Information

Phone 82-2-2228-8523 Email kchwang@yuhs.ac Website

Educational Background

Undergraduate Education M.S. Korea University Graduate School, Seoul, Republic of Korea. 1988
Final Degree (University, Major) Ph.D., Korea University Graduate School, Seoul, Republic of Korea. 1993
Overseas Training (Institute, Supervisor) -Postdoctoral Fellow in Department of Molecular Cardiology, Cleveland Clinic, OH, USA
-Senior Research Associate, The Victor Chang Cardiac Research, NSW University, Sydney, Australia

Professional Societies and current positions

2011: Senior Editorial Board, American Journal of Stem Cells (AJSC)
2011: Editorial Board, Journal of Geriatric Cardiology (JGC)
2009: Editorial Board, World Journal of Stem Cells (WJSC)
2007: Dean, Strenthening Korea’s Science & Technology Infrastructure, Basic Science Program, Korea Science and Engineering Foundation.
2006: Editor, Korean Tissue Engineering and Regenerative Medicine Society.
2005: Program Manager, Korea Research Foundation.

Research Area(s)

Basic research, Translational research, Drug trial
Research Field -Development of small molecules for application of heart disease
-Specific differentiation of mesenchymal stem cells
-Study for roles of microRNAs in artherosclerosis, cardiac hypertrophy and stem cell differentiation
-Application of mesenchymal stem cells with enhanced functions
Diseases Myocardial Infarction, Atherosclerosis, Cardiac hypertrophy, Stem cell therapy
Possible Collaboration 1)Rat myocardial Infarction model
2)Smooth Muscle Cells in atherosclerosis
3)Differentiation of mesenchymal Stem Cell
4)Cardiac Hypertrophy

Research Methods

Balloon injury model
Myocardial infarction model
Stem cell culture
Differentiation of cardiogenic cells, chondrocytes and endothelial cells
microRNA technique

Lab.

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Location of Office 심혈관병원 625호
Location of Lab. 심혈관병원 625호
Contact person Name: 강미선 / Tel: 2228-8521 / E-mail: kangmisun@yuhs.ac

Major Published Articles and Books

1) Cardiomyocytes from phorbol myristate acetate-activated mesenchymal stem cells restore eletromechanical function in infarcted rat hearts. Song H, Hwang HJ, Chang W Song BW, Cha MJ, Ham O, Lee CY, Park JH, Lee SY, Choi E, Lee C, Lee M, Lee MH, Kim SH, Jang Y, Hwang KC. Proc Natl Acad Sci U S A. 2011 Jan4;108(1):296-301.
2) Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex. Song H, Cha MJ, Song BW, Kim IK, Chang W, Lim S, Choi EJ, Ham O, Lee SY, Chung N, Jang Y, Hwang KC. Stem Cells. 2010 Mar 31;28(3):555-563.
3) Mesenchymal stem cells pretreated with delivered Hph-1-Hsp70 protein are protected from hypoxia-mediated cell death and rescue heart functions from myocardial injury. Chang W, Song BW, Lim S, Song H, Shim CY, Cha MJ, Ahn DH, Jung YG, Lee DH, Chung JH, Choi KD, Lee SK, Chung N, Lee SK, Jang Y, Hwang KC. Stem Cells. 2009 Sep;27(9)2283-2292.
4) Hwang KC, Kim JY, Chang W, Kim DS, Lim S, Kang SM, Song BW, Ha HY, Huh YJ, Choi IG, Hwang DY, Song H, Jang Y, Chung N, Kim SH, Kim DW. Search for Chemical Reagents that Regulate Stem Cell Fate. 2008. Proc Natl Acad Sci U S A. 105(21):7467-71.
5) Modification of mesenchymal stem cells for cardiac regeneration. Song H, Song BW, Cha MJ, Choi IG, Hwang KC. Expert Opin Biol Ther. 2010 Mar;10(3):309-319.