박용범 / Yong-Beom Park 교수 Department / Institute / Center : Internal Medicine (Rheumatology) Institute for Immunology and Immunologic diseases

Contact Information

Phone	82-2-2228-1967	Email	yongbpark@yuhs.ac	Website

Educational Background

Undergraduate Education	MD, Yonsei University College of Medicine, 1993
Final Degree (University, Major)	PhD, Yonsei University College of Medicine, 2004
Overseas Training (Institute, Supervisor)	University of California, San Diego, Div. of Rheumatology, Gregg Silverman, MD, 2006-2008

Professional Societies and current positions

대한류마티스학회 이사 대한류마티스학회 국제위원회, 임상위원회 의원 세브란스병원 류마티스내과장

Research Area(s)

Translational research, Clinical research, Medical devices, Drug trial

Research Field	Mesenchymal stem cell treatment in Rheumatoid arthritis and systemic lupus erythematosus Treatment of arthritis using multi-functional nanoparticle Optic imaging for arthritis Atherosclerosis and inflammation (esp, rheumatoid arthritis) Natural autoantibody Human induced pluripotent stem cells from RA and SLE patients
Diseases	Rheumatoid arthritis Systemic lupus erythematosus Vasculitis (Takayasu arteritis, Bachet disease) Gout
Possible Collaboration	류마티스 질환과 관련된 mesenchymal stem cell 연구 류마티스 관절염의 조기 진단을 위한 표지자 발굴 류마티스 관절염의 새로운 치료제 개발 Imaging for inflammation 혈관염의 병인 연구 통풍의 유전자 연구

Research Methods

Collagen induced arthritis and lupus model synovial cell and mesenchymal stem cell culture Optic imaging Single cell PCR FACS analysis, apoptosis assay Confocal microscopy Immunohistochemistry Micro-CT

Lab.

Location of Office	의대본관 306호
Location of Lab.	ABMRC 201호
Contact person	Name: 박규형 / Tel: 02-2228-0746 / E-mail: khyungpark@gmail.com

Major Published Articles and Books

1.Targeted chemo-photothermal treatments of rheumatoid arthritis using gold half-shell multifunctional nanoparticles. Lee SM, Kim HJ, Ha YJ, Park YN, Lee SK, Park YB, Yoo KH. ACS Nano. 2013 Jan 22;7(1):50-7. 2. Soluble receptor for advanced glycation end products alleviates nephritis in (NZB/NZW)F1 mice. Lee SW, Park KH, Park S, Kim JH, Hong SY, Lee SK, Choi D, Park YB. Arthritis Rheum. 2013 Jul;65(7):1902-12. 3. The role of (18) F-fluorodeoxyglucose-positron emission tomography in the assessment of disease activity in patients with takayasu arteritis. Lee KH, Cho A, Choi YJ, Lee SW, Ha YJ, Jung SJ, Park MC, Lee JD, Lee SK, Park YB. Arthritis Rheum. 2012 Mar;64(3):866-75. 4. Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. Chen Y, Khanna S, Goodyear CS, Park YB, Raz E, Thiel S, Grönwall C, Vas J, Boyle DL, Corr M, Kono DH, Silverman GJ. J Immunol. 2009 Jul 15;183(2):1346-59. 5. IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells. Chen Y, Park YB, Patel E, Silverman GJ. J Immunol. 2009 May 15;182(10):6031-43.