김한수 / Han-Soo Kim
연구부교수

Department / Institute / Center :
Department of Laboratory Medicine/ Cell Therapy Center

Contact Information

Phone 82-2228-7823 Email hansk@yuhs.ac Website

Educational Background

Undergraduate Education Kyunghee University
Final Degree (University, Major) Ph.D. (Rutgers, the State University of New Jersey, New Brunswick, New Jersey, USA, Immunology)
Overseas Training (Institute, Supervisor) Ochsner Medical Foundation, New Orleans, Lousianna, USA (Laboratory of Cellular Immunology, Yong Sung Choi, M.D., Ph.D.)

Professional Societies and current positions

International Society for Stem Cell Research, member
Korean Tissue Engineering ad Regenertive Medicine Society, member
Tissue Engineering ad Regenertive Medicine (journal), Associate Editor
Korean Society for Stem Cell Research,, member

Research Area(s)

Basic research, Translational research
Research Field 1. Dendritic cell-based cancer immunotherapy, immunopotentiation of dendritic cells
2. Translational research with mesenchymal stem cells: MSCs for stroke treatment in animal ischemic stroke model to investigate the therapeutic mechanism
3. New surface marker identification of undifferentiated human embryonic stem cells and neural progenitor cells and development of monoclonal antibody to purify those.
Diseases Solid tumor immunotherapy (research)
Stem cell-based tissue regenerative medicine/translational research
Possible Collaboration Preparation of cellular therapeutics (clinical grade) and quality control for immunotherapy and stem cell-based therapy

Research Methods

Specific cell subset purification by MACS
Gene cloning
Human mononuclear cell isolation
Human mesenchymal stem cell isolation
Immunophenotyping of cells, FACS analysis
Cell proliferation assay

Lab.

연구실사이트 바로가기
Location of Office 2nd floor, College of Medicine (Old wing)
Location of Lab. Medical Research Center 101
Contact person Name: Seongmi Choi / Tel: 2228-2797 / E-mail: seongmc@daum.net

Major Published Articles and Books

1. Kim, H.J., Kim, H-O., Baek, E.J., Lee, K.W. and Kim, H.-S. 2010. Two-step maturation of immature DCs with proinflammatory cytokine cocktail and poly(I:C) enhances migratory and allostimulatory capacity with high IL-12 production. Vaccine 28; 2877–2886.

2. Kim, S., Kim, H.O., Kim, H.J., Lee, K, and Kim, H.-S. 2008. Generation of functionally mature dendritic cells from elutriated monocytes using poly(I:C) and soluble CD40 ligand for clinical application. Clinical and Experimental Immunology 154: 365-374

3. Kim, H.-S., Choo, Y.S., Koo, T., Bang, S. Oh, T.Y., Wen, J. and Song, S.Y. 2006. Enhancement of antitumor immunity of dendritic cells pulsed with heat-treated tumor lysate in murine pancreatic cancer. Immunol. Lett. 103:142-148.

4. Kim, H-S., Choi, D-Y., Yun, S.J., Choi, S-M., Kang, J.W., Jung, J.W., Hwang, D., Kim, K.P., Kim, D-W. 2012. Proteomic analysis of microvesicles derived from human mesenchymal stem cells. J. Proteome Res. 11: 839-849.

5. Jung, M.Y., Kim, H-S., Hong, H-J., Youn, B-S and Kim, T.S. 2012. Adiponectin induces dendritic cell activation via PLCγ/JNK/NF-κB pathways, leading to Th1 and Th17 polarization. J. Immunol. 188:2592-2601.