강석구 / Seok-Gu Kang
임상부교수

Department / Institute / Center :
Neurosurgery, Brain Tumor Translational Research Lab.
Institute: Severance Hospital

Contact Information

Phone +82-2-10-2297-1108 Email seokgu9@yuhs.ac Website

Educational Background

Undergraduate Education M. D., The Catholic University of Korea College of Medicine, 1995
Final Degree (University, Major) Ph.D., Graduate School, The Catholic University of Korea, 2005
Overseas Training (Institute, Supervisor) Postdoc fellow M. D. Anderson Cancer Center, Brain Tumor Center, Houston, Texas, USA (Frederick F. Lang, M.D. 2007-2009)

Professional Societies and current positions

대한신경외과학회, 학술간사, 2010-현재
대한소아신경외과학회, 감사, 2011-현재
Society for Neuro-Oncology, Member 2006-현재
International Society for Pediatric Neurosurgery, Member 2003-현재
Childs Nervous System, Chief Editor Assistant, 2005-현재

Research Area(s)

Translational research, Clinical research
Research Field Tumor microenviroment
Mesenchymal stem cells in tumor stroma
Cancer stem cells
New therapeutic target discovery in brain tumor
Diseases brain tumor, Metastatic brain tumor, cancer
Possible Collaboration Preclinical study for brain tumor or metastatic brain tumor (뇌종양과 연관된 모든 전임상실험)
New target discovery for glioma or metastatic brain tumor
Brain tumor translational research, metastatic brain tumor translational research

Research Methods

Orthopotic brain tumor xenograft
Single cell isolation and culture from brain and brain tumors
MSCs isolation from brain tumors
Cancer stem cell isolation and culture from brain tumors
Immunocytochemistry and Immunohistochemistry for specific marker
FACS analyss and proliferation and apoptosis and micro-vascular proliferation assay
Invasion and migration assay
Mesechymal and neural differentiation technique of specific cells.

Lab.

연구실사이트 바로가기
Location of Office 의대 구관 502호
Location of Lab. 임상의학연구소로 이전 예정 (2013년)
Contact person Name: 이지현 / Tel: 010-9158-7950 / E-mail: LEE_JIHYUN@yuhs.ac

Major Published Articles and Books

Isolation of glioma cancer stem cells in relation to histological grades in glioma specimens. Childs Nerv Syst. 2012 Nov (DOI) 10.1007/s00381-012-1964-9

Changes in the biological characteristics of glioma cancer stem cells after serial in vivo subtransplantation. Childs Nerv Syst. 2012 (DOI) 10.1007/s00381-012-1963-x

Presence of glioma stroma mesenchymal stem cells in a murine orthotopic glioma model. Childs Nerv Syst. 2011 Jun;27(6):911-22.

Isolation and Perivascular Localization of Mesenchymal Stem Cells From Mouse Brain. Neurosurgery. 2010 Sep;67(3):711-20.

Cytotoxicity of human umbilical cord blood-derived mesenchymal stem cells against human malignant glioma cells. Childs Nerv Syst. 2008 Mar;24(3):293-302.