김유선 / Kim, Yu Seun
교수

Department / Institute / Center :
Research Institute for Transplantation/
Department of Transplantation Surgery

Contact Information

Phone +82-2-2228-2115 Email yukim@yuhs.ac Website

Educational Background

Undergraduate Education M.D., Yonsei University College of Medicine, 1979
Final Degree (University, Major) Ph.D., Graduate School, Korea university, 1994
Overseas Training (Institute, Supervisor) 미국 미네소타대학병원 및 장기이식부
영국 버밍검대학 Qeen Elizabeth Hospital

Professional Societies and current positions

대한이식학회 학술위원회, 위원장 (2007-현재)
연세대학교 BK21 세포기반 나노이식재 연구팀(융합), 참여교수 (2006-현재)
세브란스 장기이식센터, 교수 (2003-현재)
대한이식학회 편집위원회, 위원장 (2005-2007)
대한 이식학회, 이사장 (2011-현재)

Research Area(s)

Basic research, Translational research, Clinical research
Research Field Islet and Pancreas Transplantation
Transplantation Immunology
Toxic effects of immunosuppressive drug in transplantation
Diseases Organ and cell transplantation
Transplantation Immunology
immunosuppressive drug
Possible Collaboration 췌장 및 췌도 이식과 관련한 artificial tissue 연구
베타세포의 인슐린 분비능 증대를 위한 stem cell 연구
면역억제제의 세포독성 기전 연구 및 방어기작 연구
신장이식 시 사구체내 족세포 변화 기전 연구

Research Methods

primary islet isolation and culture (rat, pig, dog, mouse)
Rat primary hepatocyte isolation and culture
Primary glomerulus isolation
Immotalized mouse podocyte culture
Immunocytochemistry, immumohistochemistry
Western blotting, Immunoprecipitation
MTT assay, LDH assay, TUNEL assay, FACS analysis
siRNA transfection
PCR, real-time PCR
Glucose challenge test
Chondrocyte, MSC isolation and culture
Cell sheeting engineering and 3D culture
Diabetes mellitus induction

Lab.

연구실사이트 바로가기
Location of Office 러들로 교수동 2층
Location of Lab. 의대본관 3층 장기이식연구소
Contact person Name: 조유리 / Tel: 02)2228-5373 / E-mail: yuricho99@gmail.com

Major Published Articles and Books

1. Ha H, Kim MS, Park JH, Huh JY, Huh KH, Ahn HJ, Kim YS (corresponding). Mycophenolic acid inhibits mesangial cell activation through p38 MAPK inhibition. Life Sciences 2006:79:1561-7
2. Park YJ, Ahn HJ, Chang HK, Kim JY, Huh KH, Kim MS, Kim YS (corresponding). The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line. Cellular Signalling 2009:21:356-64
3. Kang ES, Kim MS, Kim CH, Nam CM, Han SJ, Hur KY, Ahn CW, Cha BS, Kim SI, Lee HC, Kim YS(corresponding). Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea. Transplantation 2009:88(5):693-8
4. Kim JY, Lee JI, Jeong JH, Fang Y, Ju MK, Kim SJ, Huh KH, Kim MS, Kim YS(corresponding). Improved yield and functional parameters of rat pancreas islets isolated under intramuscular anesthesia. Cell Transplant. 2010:19(6):743-50
5. Huh KH, Kim MS, Kim HJ, Joo DJ, Kim BS, Ju MK, Kim SI, Kim YS(corresponding). Renal transplantation in sensitized recipients with positive luminex and negative CDC (complement-dependent cytotoxicity) crossmatches. Transpl Int. 2012:25(11):1131-7