김경섭 / Kyung-Sup Kim
교수

Department / Institute / Center :
Dept. of Biochem. & Mol. Biol./ Integrated genomic research centre for metabolic regulation

Contact Information

Phone +82-2228-1676 Email kyungsup59@yuhs.ac Website http://biochemistry.yonsei.ac.kr/

Educational Background

Undergraduate Education Yonsei University College of Medicine
Final Degree (University, Major) Ph.D.(Yonsei Univiersity, Medical science)
Overseas Training (Institute, Supervisor) Overseas Training
(Institute, Supervisor) Dept of Biochemistry, Purdue University

Professional Societies and current positions

Professor of department of biochemistry and molecular biology
Vice dean of research field
Director of integrated genomic research center for metabolic regulation (MRC)

Research Area(s)

Basic research
Research Field Study to elucidate the metabolic regulations in normal physiological condition or metabolic disease states including diabetes and various cancers.
Diseases Diabetes, obesity, cancers
Possible Collaboration Endocrinology, oncology, and medical imaging using metabolic profiling

Research Methods

Forced expression or knock/down of specific genes.
Estimating the promoter activities of specific genes
Estimating the translational control of specific transcripts
Measuring the activity of various metabolic enzymes

Lab.

연구실사이트 바로가기
Location of Office 의과대 신관 501호
Location of Lab. 의과대 신관 501호
Contact person Name: 고은진 / Tel: 82-2228-1677 / E-mail: kohchun@yuhs.ac

Major Published Articles and Books

Koh YK, Lee MY, Kim JW, Kim M, Moon JS, Lee YJ, Ahn YH, Kim KS. 2008. Lipin1 Is a Key Factor for the Maturation and Maintenance of Adipocytes in the Regulatory Network with CCAAT/Enhancer-binding Protein {alpha} and Peroxisome Proliferator-activated Receptor {gamma}2. J Biol Chem 283: 34896-34906.
Lee MY, Moon JS, Park SW, Koh YK, Ahn YH, Kim KS. 2009. KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cell line. Biochem J 417: 313-322.
Moon JS, Jin WJ, Kwak JH, Kim HJ, Yun MJ, Kim JW, Park SW, Kim KS. 2010. Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells. Biochem J 433: 225-233.
Moon JS, Kim HE, Koh E, Park SH, Jin WJ, Park BW, Park SW, Kim KS. 2011. Kruppel-like Factor 4 (KLF4) Activates the Transcription of the Gene for the Platelet Isoform of Phosphofructokinase (PFKP) in Breast Cancer. J Biol Chem 286: 23808-23816.