박형천 / PARK, Hyeong-Cheon
부교수

Department / Institute / Center :
Internal Medicine (Nephrology)
Gangnam Severance Hospital
Severance Institute for Vascular and Metabolic Research

Contact Information

Phone +82-2-2019-3310 Email amp97@yuhs.ac Website

Educational Background

Undergraduate Education M.D., Yonsei University College of Medicine, 1992
Final Degree (University, Major) Ph.D., Graduate School, Yonsei University, 2000
Overseas Training (Institute, Supervisor) New York Medical College, Renal Research Institute,
Michael S. Goligorsky, MD, PhD, 2006.7. – 2008. 6.

Professional Societies and current positions

대한내과학회, 회원
대한신장학회, 보헙법제위원, 재무위원
American Society of Nephrology, Member, 2000-현재
International Society of Nephrology, Member, 2000-현재
American Society of Physiology, Member, 2009-현재

Research Area(s)

Basic research, Translational research, Clinical research, Drug trial
Research Field Role of stem cells in renal regeneration
Application of kidney derived mesenchymal stem cell in acute kidney injury
Role stem cell derived microparticles in kidney vascular regeneration
Diseases acute kidney injury, renal stem cell, stem cell derived microparticles
Possible Collaboration 줄기세포를 이용한 신부전증 치료 기전 규명
줄기세포 유래 미세입자를 이용한 신부전증 치료
신장 유래 줄기세포를 이용한 조혈인자 생성 기전 탐색

Research Methods

Mouse kidney derived stem cell isolation and culture
HUVEC culture and differentiation
Confocal microscopy, immunohistochemistry
FACS analysis, apoptosis assay
kidney ischemia-reperfusion injury experiment
Unilateral ureteral obstruction experiment

Lab.

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Location of Office 강남세브란스병원 별관 8층
Location of Lab. 강남세브란스병원 의생명연구센터 2층 (혈관대사연구센터)
Contact person Name: / Tel: 2019-5326 / E-mail: amp97@yuhs.ac

Major Published Articles and Books

1) Renal capsule as a stem cell niche Park HC*, K Yasuda, Kuo MC, Ni J, Ratliff BB, Chander PN, Goligorsky MS. Am J Physiol Renal Physiol. 2010 298; F1254-1262.
2) Adriamycin nephropathy. A failure of endothelial cell-induced repairs. Yasuda K*, Park HC*, B Ratliff, Addabbo F, Hatzopoulos AK, Chander PN, Goligorsky MS. Am J Pathol. 2010 176(4):1685-1695.
3) Postobstructive regeneration of kidney is derailed when surge in renal stem cells. Park HC*, K Yasuda, B Ratliff, A Stoessel, Y Sharkovska, I Yamamoto, JF Jasmin, S Bachman, MP Lisanti, P Chander, MS Goligorsky. Am J Physiol Renal Physiol. 2010 298; F357-364
4) Urinary TGF-beta1 as an indicator of antiproteinuric response to angiotensin II receptor blocker in proteinuric renal diseases. Park HC*, Choi HY, Kim BS, An HR, Lee JS, Ha SK, Han DS. Biomed Pharmachother. 2009 63; 672-678
5) Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair. Chen J, Park HC*, Addabbo F, Ni J, Pelger E, Li H, Plotkin M,Goligorsky MS. Kidney Int. 2008 74(7); 879-889