박채규 / Park, Chae Gyu
부교수

Department / Institute / Center :
Severance Biomedical Science Institute
의생명과학부

Contact Information

Phone +82-2-2228-0795 Email ChaeGyu@yuhs.ac Website

Educational Background

Undergraduate Education B.Sc., Seoul National University, 1990
Final Degree (University, Major) Ph.D., Rockefeller University (Laboratory of Immunology), 1997
Overseas Training (Institute, Supervisor) Harvard Medical School (1999-2000)
Rockefeller University (2000-2013)

Professional Societies and current positions

Member, International Society for Dendritic Cell and Vaccine Science, 2010
Member, Harvey Society, 2007

Research Area(s)

Basic research, Translational research
Research Field Initiation, regulation, and memory of immune responses
Function of dendritic cells and macrophages
Function of C-type lectin and pattern recognition receptors in immune system
Immune surveillance mechanisms in healthy and diseased states
Development and preclinical study of dendritic cell-based vaccines
Diseases Immune responses in various infection and chronic diseases
Cancers
Possible Collaboration On immune response mechanisms

Research Methods

Dendritic cell isolation and culture
Analysis of immune responses with model antigens
Flow cytometric analysis
Recombinant protein expression in mammalian cells

Lab.

연구실사이트 바로가기
Location of Office ABMRC 325호
Location of Lab. ABMRC 326호
Contact person Name: 나혜영 / Tel: 2228-0938 / E-mail: hyeyna@yuhs.ac

Major Published Articles and Books

1)The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen. Kang Y-S, Kim JY, Bruening SA, Pack M, Charalambous A, Pritsker A, Moran TM, Loeffler JM, Steinman RM, Park CG. 2004. Proc. Natl. Acad. Sci. U. S. A. 101:215-220. (교신저자)
2)A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q. Kang Y-S, Do Y, Lee H-K, Park SH, Cheong C, Lynch RM, Loeffler JM, Steinman RM, Park CG. 2006. Cell. 125:47-58. (교신저자)
3)Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves. Choi JH, Do Y, Cheong C, Koh H, Boscardin SB, Oh YS, Bozzacco L, Trumpfheller C, Park CG, Steinman RM. 2009. J. Exp. Med. 206:497-505. (교신저자)
4)Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209+ dendritic cells for immune T cell areas. Cheong C, Matos I, Choi JH, Dandamudi DB, Shrestha E, Longhi MP, Jeffrey KL, Anthony RM, Kluger C, Nchinda G, Koh H, Rodriguez A, Idoyaga J, Pack M, Velinzon K, Park CG, Steinman RM. 2010. Cell. 143:416-429. (교신저자)
5) Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody. Cheong C, Choi JH, Vitale L, He LZ, Trumpfheller C, Bozzacco L, Do Y, Nchinda G, Park SH, Dandamudi DB, Shrestha E, Pack M, Lee HW, Keler T, Steinman RM, Park CG. 2010. Blood. 116:3828-3838. (교신저자)