홍사민 / Hong, Samin
임상조교수

Department / Institute / Center :
Ophthalmology
Institute of Vision Research
EYE-ENT Center
안과
시기능개발연구소
안이비인후과병원

Contact Information

Phone +82-2228-3591 Email samini@yuhs.ac Website

Educational Background

Undergraduate Education M.D., Yonsei University College of Medicine, 2003
Final Degree (University, Major) Ph.D., Graduate school, Yonsei University College of Medicine, 2010
Overseas Training (Institute, Supervisor) Gifu Pharmaceutical University, Gifu, Japan
(Supervisor: Hideaki Hara, PhD, RPh)
New York Eye and Ear Infirmary, New York, NY, USA
(Supervisor: Robert Ritch, MD)
DNAVEC Corporation, Tsukuba, Japan
(Supervisor: Mamoru Hasegawa, PhD)

Professional Societies and current positions

한국녹내장학회
한국신경안과학회
World Glaucoma Association
Association for Research in Vision and Ophthalmology
International Symposium on Ocular Pharmacology and Therapeutics (Board member)

Research Area(s)

Basic research, Translational research, Clinical research, Drug trial
Research Field Neuroprotection & neuroregeneration of optic nerve
Axonal growth & guiding of neurons
Diseases Glaucoma, Optic neuropathy, Neurodegeneration, Neuroregeneration
Possible Collaboration 녹내장 및 시신경병증의 기전 탐구 및 치료법 개발
줄기세포를 이용한 신경 보호 및 재생

Research Methods

Human dental pulp stem cell culture & differentiation
Primary mouse retinal ganglion cells culture
Primary mouse Muller glia & astrocytes culture
Middle cerebral artery occlusion animal model
Optic nerve crush animal model
Chronic & acute ocular hypertension animal model
Other molecular works (RT-PCR, Western blots, immunofluorescence, ELISA, TUNEL, etc.)

Lab.

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Location of Office 러들로교수동 303호
Location of Lab. 안이비인후과병원 B2 시기능개발연구소
Contact person Name: 이주카요코 / Tel: 2228-3636 / E-mail: yang_ja@yuhs.ac

Major Published Articles and Books

1) Retroviral expression of human arginine decarboxylase reduces oxidative stress injury in mouse cortical astrocytes. Hong S, Son MR, Yun K, Lee WT, Park KA, Lee JE. BMC Neurosci. 2014;15:99.
2) Isolation of primary mouse retinal ganglion cells using immunopanning-magnetic separation. Hong S, Iizuka Y, Kim CY, Seong GJ. Mol Vis 2012;18:2922-2930.
3) Ocular hypotensive effects of topically administered agmatine in a chronic ocular hypertensive rat model. Hong S, Kim CY, Lee WS, Shim J, Yeom HY, Seong GJ. Exp Eye Res 2010;90(1):97-103.
4) Adjusted peripapillary retinal nerve fiber layer thickness measurements based on the optic nerve head scan angle. Hong S, Kim CY, Seong GJ. Invest Ophthalmol Vis Sci. 2010;51(8):4067-74.
5) Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line. Hong S, Lee JE, Kim CY, Seong GJ. BMC Neurosci 2007;8:81.