박영년 / PARK, Young Nyun
교수

Department / Institute / Center :
Department of Pathology
만성대사성질환연구센터
Institute of Gastroenterology

Contact Information

Phone +82-2-2228-1768 Email young0608@yuhs.ac Website

Educational Background

Undergraduate Education M.D., Yonsei University College of Medicine, 1987
Final Degree (University, Major) Ph.D., Graduate School, Yonsei University, 1994
Overseas Training (Institute, Supervisor) Department of Pathology, Mount Sinai Medical Center, USA
Swan Thung, MD, 1995

Professional Societies and current positions

PLoS One, academic editor, 2010 ~ 현재
Hans Popper Hepatopathology Society, Educational committee chair, 2009-2011
한국과학기술한림원, 정회원, 2010 ~ 현재
대한병리학회, 편집위원
대한간학회 학술위원

Research Area(s)

Basic research, Translational research, Clinical research
Research Field Pathogenesis of multistep hepatocarcinogenesis
Development of diagnostic markers for early HCC
Development of prognostic markers for progressed HCC
Application of cancer stem cell in hepatobiliary tumor
Identification of liver stem cell in chronic liver disease
Diseases Hepatocellular carcinoma, dysplasia, cirrhosis, stem cell, NAFLD and telomere
Possible Collaboration 간암조직의 프로테옴/지노믹스를 이용한 신약타겟 및 예후인자 발굴
간암의 조기진단을 위한 표지마커의 발굴
간암에 관련된 모든 세포생물학적 연구
만성간질환의 간줄기세포의 활성화 기전

Research Methods

Pathology, FISH, immunohistochemistry, Confocal microscopy, FACS analysis, real time PCR, EM

Lab.

연구실사이트 바로가기
Location of Office 의대본관 237호
Location of Lab. 임상연구센터 405호
Contact person Name: 나득채(박사과정), / Tel: 2228-2692 / E-mail:

Major Published Articles and Books

Yoon SM, Gerasimidou D, Kuwahara R, Hytiroglou P, Yoo JE, Park YN, Theise ND. Epithelial Cell Adhesion Molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans. Hepatology 2011;53:964-973
Um T-H, Kim H, Oh B-K, Kim MS, Kim KS, Jung G, Park YN. Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis. J Hepatol 2011 [ in press]
Kim H, Oh B-K, Roncalli M, Park C, Yoon S-M, Yoo JE, Park YN. Large liver cell change in hepatitis B virus–related liver cirrhosis. Hepatology 2009 May 11;50(3):752-762
Di Tommaso L, Destro A, Seok JY, Balladore E, Terracciano L, Sangiovanni A, Iavarone M, Colombo M, Jang JJ, Yu E, Jin SY, Morenghi E, Park YN, Roncalli M. The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma. J Hepatol. 2009 Apr;50(4):746-54
Oh BK, Kim H, Park YN, Yoo JE, Choi J, Kim KS, Lee JJ, Park C. High telomerase activity and long telomeres in advanced hepatocellular carcinomas with poor prognosis. Laboratory Investigation 2008; 88:144–152