이영호 / LEE, Young-Ho
교수

Department / Institute / Center :
Physiology
생리학

Contact Information

Phone : +82-2-2228-1708 Email yhlee@yuhs.ac Website

Educational Background

Undergraduate Education D.V.M., Kyung Pook National University, College of Veterinary Medicine, 1985
Final Degree (University, Major) Ph.D., Kyung Pook National University, College of Veterinary Medicine, 1985
Overseas Training (Institute, Supervisor) Boston Biomedical Research Institute
Kathleen G. Morgan, Ph.D., 1998-1999

Professional Societies and current positions

대한생리학회, 학술위원, 2008-present
한국평활근학회, 운영위원, 1998-present
American Physiological Society, regular member, 1996-present
Biophysical Society, regular member, 2001-present

Research Area(s)

Basic research
Research Field Excitation-contraction coupling in vascular smooth muscle
Relationship between changes of vascular tone and vascular diseases
Identification of a proteins involved in hypertension
Diseases Hypertension, Atherosclerosis, vasospasm
Possible Collaboration 고혈압 유발 인자 발굴
혈관 질환 유발 유전체 발굴

Research Methods

Tension recording of vascular tissues
Vessel diameter measurement (Lumen/Media ratio, wall thickness)
Intracellular calcium measurement in single cell or whole tissue
Imaging study with specific antibody in single vascular smooth muscle cell

Lab.

연구실사이트 바로가기
Location of Office 의대 신관 4층 401호
Location of Lab. 의대 신관 4층 401호 –생리학교실
Contact person Name: 임미화(조교), / Tel: 2228-1726 / E-mail: mhleem2010

Major Published Articles and Books

1) Choi SK, Ahn DS, Lee YH. Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery. Cardiovasc Res 2009;82:324-332
2) Cho YE, Ahn DS, Kim YH, Taggart MJ, Lee YH. Changes in stretch-induced tone induced by intracellular acidosis in rabbit basilar artery: Effects on BKCa channel activity. Vascular Pharmacology 2007;47(1):74-82
3) Ahn DS, Choi SK, Kim YH, Cho YE, Shin HM, Morgan KG, Lee Y-H. Enhanced stretch-induced myogenic tone in the basilar artery of spontaneously hypertensive rats. J Vasc Res 2007; 44:182-191
4) Dong-Soo Yeon, Jung-Sup Kim, Duck-Sun Ahn, Seong-Chun Kwon, Bok-Soon Kang, Kathleen G Morgan, Young-Ho Lee. Role of protein kinase C- or RhoA-induced Ca2+ sensitization in stretch-induced myogenic tone. Cardiovas Res 2002;53:431-438
5) Young-Ho Lee, Cynthia Gallant, HongQui Guo, Yanhua Li, C.-L. Albert Wang, and Kathleen G. Morgan. Regulation of vascular smooth muscle tone by N-terminal region of caldesmon: Possible role of tethering actin to myosin. J Biol Chem 2000;275(5):3213-3220