임중우 / LEAM, Joong Woo
교수

Department / Institute / Center :
Physiology

Contact Information

Phone +82-2-2228-1709 Email jwleem@yuhs.ac Website

Educational Background

Undergraduate Education M.S., Sogang University, 1978
Final Degree (University, Major) Ph.D., Graduate School, University of Texas Medical Branch, 1991(Major in Neuroscience)
Overseas Training (Institute, Supervisor) Marine Biomedical Institute, University of Texas Medical Branch,
Jin Mo Chung, Ph.D., 1991-1993

Professional Societies and current positions

- 대한생리학회, 운영위원, 1983-현재
- 한국뇌신경과학회, 2004-현재
- Society for Neuroscience, Member, 1988-현재
- International Brain Research Organization, 1988-현재
- American Pain Society, Member, 2006-현재

Research Area(s)

Basic research, Translational research
Research Field - Somatosensoty system in mammalian nervous system
- Synaptic plasticity in periphery; neuropathic pain models
- Cell transplantation therapy
Diseases - Neural mechanisms of Neuropathic Pain
- Electroacupucture for pain management
- Cell transplantation for the management of neuropathic pain
Possible Collaboration - Investigation of the underlying mechanisms of neuropathic pain
- Searching for therapeutic means to treat pathological pain syndromes using
electroacupuncture, drug delivery, and cell transplantation techniques

Research Methods

- Extracellular recordings for single nerve impulses
- Single fiber recordings
- Fabrication of various animal models for pathological pain
- Behavioral testing for pain-like behaviors developing in rats and mice
- Immunohistochemistry, in situ hybridization
- Stereology analysis for cell counts
- Cell transplantation using the modified lumbar puncture technique
- Western blot analysis, ELISA

Lab.

연구실사이트 바로가기
Location of Office 의대신관 401-7호
Location of Lab. 임상연구센타 216호
Contact person Name: 정세정(조교), / Tel: 2228-1727 / E-mail:

Major Published Articles and Books

- Kim D-S, Jung SJ, Nam TS, Jeon YH, Lee DR, Lee JS, Leem JW, Kim D-W (2010) Transplantation of GABAergic neurons from ES cells attenuates tactile hypersensitivity following spinal cord injury. Stem Cells 28: 2099-2108.
- Jang JH, Lee BH, Nam TS, Kim JW, Kim D-W, Leem JW (2010) Peripheral contributions to the mechanical hyperalgesia following a lumbar 5 spinal nerve lesion in rats. Neuroscience 165: 221-232.
- Gwak YS, Kim HK, Kim HY, Leem JW (2010) Bilateral hyperexcitability of thalamic VPL neurons following unilateral spinal injury in rats. J Physiol Sci 60: 59-66.
- Jang JH, Kim KH, Nam TS, Lee WT, Park KA, Kim D-W, Leem JW (2007) The role of uninjured C-afferents and injured afferents in the generation of mechanical hypersensitivity after partial peripheral nerve injury in the rat. Exp Neurol 204: 288-298.
- Gwak YS, Tan HY, Nam TS, Paik KS, Hulsebosch CE, Leem JW (2006) Activation of spinal GABA receptors attenuates chronic central neuropathic pain after spinal cord injury. J Neurotraum 23: 1111-1124.
- Shim B, Kim D-W Kim BH, Nam TS, Leem JW, Chung JM (2005) Mechanical and heat sensitization of cutaneous nociceptors in rats with experimental peripheral neuropathy. Neuroscience 132: 193-201.