김경환 / KIM, Gyung-whan
부교수

Department / Institute / Center :
Neurology

Contact Information

Phone +82-2-2228-1609 Email gyungkim@yuhs.ac Website

Educational Background

Undergraduate Education M.D., Yonsei University College of Medicine, 1981
Final Degree (University, Major) Ph.D., Graduate School, Yonsei University, 1994(Yonsei University, Medicine(neurology))
Overseas Training (Institute, Supervisor) UC San Francisco, CA, USA, Dept. neurology
Stanford university, CA, USA, Dept. neurology
(P. Chan, PhD, 1997-2001)

Professional Societies and current positions

Vascular Neurology, 회장, 2009-2011


Research Area(s)

Basic research, Translational research, Clinical research
Research Field In vivo study for curing vascular neurology disease
Mornitoring and blood study for old aged patients who took arterial disease
Diseases stroke, arterial disease
Possible Collaboration 뇌졸중 조기진단을 위한 표지마커의 발굴
뇌졸중에 관련된 모든 세포생물학적 연구
혈관의 혈전생성 메커니즘연구 및 치료방법 개발

Research Methods

Transient cerebral ischemia model in mouse
siRNA, adenoviral gene transfer
Confocal microscopy, immunohistochemistry
FACS analysis, apoptosis assay

Lab.

연구실사이트 바로가기
Location of Office 의대본관 532호
Location of Lab. 임상연구센터 221호(유전체연구센터)
Contact person Name: 조경주(책임연구원 / Tel: 2228-1602 / E-mail: nehemier@msn.com

Major Published Articles and Books

1) Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice. Heo, K., Cho, Y.J., Cho, K.J., Kim, H.W., Kim, H.J., Shin, H.Y., Lee, B.I., Kim, G.W., 2006. Neurosci Lett. 398, 195-200.
2) Post-ischemic administration of peptide with apurinic/apyrimidinic endonuclease activity inhibits induction of cell death after focal cerebral ischemia/reperfusion in mice. Kim, H.W., Cho, K.J., Lee, B.I., Kim, H.J., Kim, G.W., 2009b. Neurosci Lett. 460, 166-9.
3) The adenoviral vector-mediated increase in apurinic/apyrimidinic endonuclease inhibits the induction of neuronal cell death after transient ischemic stroke in mice. Kim, H.W., Cho, K.J., Park, S.C., Kim, H.J., Kim, G.W., 2009c. Brain Res. 1274, 1-10.
4) Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease. Cho, K.J., Lee, B.I., Cheon, S.Y., Kim, H.W., Kim, H.J., Kim, G.W., 2009. Neuroscience. 163, 1128-34.
5) The role of MMP-9 in integrin-mediated hippocampal cell death after pilocarpine-induced status epilepticus. Kim, G.W., Kim, H.J., Cho, K.J., Kim, H.W., Cho, Y.J., Lee, B.I., 2009a. Neurobiol Dis. 36, 169-80.