윤진숙 / YOON, Jin Sook
조교수

Department / Institute / Center :
Ophthalmology/ Yonsei University College of Medicine / EYE-ENT center

Contact Information

Phone +82-2228-3586 Email yoonjs@yuhs.ac Website

Educational Background

Undergraduate Education Yonsei University College of Medicine, 2000
Final Degree (University, Major) PhD. Graduate school, Yonsei University, 2010
Overseas Training (Institute, Supervisor) Mayo Clinic
Dr. Garrity JA
Department of Ophthalmology, 2007

Professional Societies and current positions

대한안성형학회 정회원, 대한안과학회 정회원
ARVO학회 회원, AAO 회원

Research Area(s)

Basic research, Clinical research
Research Field In vitro and clinical research of Graves’ orbitopathy
: Investigation of a new drug for Graves’ orbitopathy
Diseases Graves’ orbitopathy, Orbital disease including inflammatory, autoimmune disease
Lacrimal passage disorder, Malignant orbital tumor
Possible Collaboration Graves’ orbitopathy관련된 모든 연구 – in vitro using orbital fibroblasts from GO and clinical research (risk factor analysis, Quality of life questionnaire, thyroid hormone receptor antibody와 clinical severity와의 correlation 등 endocrinologist의 관심과 협조가 필요)

Research Methods

1. in vitro culture of orbital fibroblasts from orbital tissue of GO
2. inflammation유도, hyaluronan production 측정 by ELISA
3. Adipogenesis 유도
4. Quercetin, Resveratrol과 같은 신약 in vitro에서의 효과 실험에 대한 경험.
5. 그외, Apoptosis (annexin V/FITC), MTT, BrDU assay, ROS measurement (DCFDA)
Cigarette smoking extract 를 이용한 실험
GO orbital tissue를 RNA later, -70C에 모으고 있음. – RNA 추출, DNA 분석가능

Lab.

연구실사이트 바로가기
Location of Office 러들러교수동 310
Location of Lab. 임상의학연구센터 322호
Contact person Name: 최수현 / Tel: 2228-2810 / E-mail: : TNGUS1202@yuhs.ac

Major Published Articles and Books

Risk factors associated with the severity of thyroid-associated orbitopathy in Korean patients. Lee JH, Lee SY, Yoon JS. Korean J Ophthalmol. 2010 Oct;24(5):267-73
Assessment of quality of life and depression in Korean patients with Graves' ophthalmopathy. Lee H, Roh HS, Yoon JS, Lee SY. Korean J Ophthalmol. 2010 Apr;24(2):65-72
Ocular surface inflammation, and nerve growth factor level in tears in active thyroid-associated ophthalmopathy. Yoon JS, Choi SH, Lee JH, Lee SJ, Lee SY. Graefes Arch Clin Exp Ophthalmol. 2010 Feb;248(2):271-6.