김주영 / KIM, Joo Young
조교수

Department / Institute / Center :
Pharmacology

Contact Information

Phone +82-2-2228-1734 Email jooyoungkim@yuhs.ac Website

Educational Background

Undergraduate Education B.S., Yonsei University College of Medicine, 1998
Final Degree (University, Major) Ph.D, (Graduate School, Yonsei University, 2003, Cell biology and Pharmacology
Overseas Training (Institute, Supervisor) UT Southwestern Medical center at Dallas, USA (Shmuel Muallem, PhD, 2004-2006)

Professional Societies and current positions

한국분자세포생물학회 회원
대한 약리학회 회원
대한 생리학회 회원

Research Area(s)

Basic research, Translational research
Research Field Calcium signaling Mechanism
Role of calcium channel and its modulator WNK4 in hypertension
Membrane protein trafficking pathway and its modulator
Diseases Hypertension, Pancreatitis, disease altered by membrane protein targeting
Possible Collaboration 칼슘 신호측정을 이용한 각 시스탬에서의 칼슘신호전달과정, Hypertension 관련 인자의 분자기전 연구, 단백의 세포내 위치 확인 연구, Microglia의 뇌면역반응 활성연구

Research Methods

Intracellular calcium measurement
Mouse primary microglia isolation and culture
Confocal microscopy, immunohistochemistry
Protein localization characterization( GFP fusion protein and cell fractionation assay)
Ca2+ uptake measurement using 45Ca2+(SERCA activity)
Trans cellular & intracellular uptake of ion or organic compounds
microRNA technique
Recombinant protein preparation
ATPase assay, phagocytosis assay
Non-invasive Blood pressure measurement

Lab.

연구실사이트 바로가기
Location of Office 의대신관 302호
Location of Lab. 의대신관 305호
Contact person Name: 정우영(박사1학기) / Tel: 2228-2686 / E-mail: fine22@yuhs.ac

Major Published Articles and Books

1) WNK4 kinase negatively regulates the surface expression of Muscarinic M3 receptor. Cell Signal. 2011 Mar;23(3):566-71
2) Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane. J Biol Chem. 2006 Oct 27;281(43):32540-9.
3) STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels.
Nat Cell Biol. 2006 Sep;8(9):1003-10. Epub 2006 Aug 13.
4) Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells. Gastroenterology. 2002 Jun;122(7):1941-53.
5) Inhibitory regulation of cystic fibrosis transmembrane conductance regulator anion-transporting activities by Shank2. J Biol Chem. 2004 Mar 12;279(11):10389-96.